Journal
TETRAHEDRON
Volume 61, Issue 11, Pages 2761-2766Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2005.01.089
Keywords
natural product synthesis; sesquiterpenoids
Categories
Ask authors/readers for more resources
Sesquiterpenoids (+)-trans-dracuncuflifoliol (1) and (+)-4-hydroxyoppositan-7-one (2) were prepared stereoselectively from enantiomerically pure (7aR)-7a-methyl-1,2,5,6,7,7a-hexahydro-4H-inden-4-one ((-)-6), whose synthesis was described herein. Conjugate addition of the organocopper (1) reagent 10 to (-)-6, followed by epimerization of the ring junction, generated 3 of the 4 contiguous chiral centers of both natural products. (c) 2005 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available