4.8 Article

Preparation of enamides via palladium-catalyzed amidation of enol tosylates

Journal

ORGANIC LETTERS
Volume 7, Issue 6, Pages 1185-1188

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol050117y

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[GRAPHICS] A Pd-catalyzed coupling of enol tosylates and amides has been developed. Ligand screening revealed dipf as the most general ligand for this transformation. A variety of enol tosylates were coupled to an array of enamides in 58-97% yield.

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