Journal
FEBS LETTERS
Volume 579, Issue 8, Pages 1789-1794Publisher
WILEY
DOI: 10.1016/j.febslet.2005.02.009
Keywords
spatial modeling; stochastic simulation; reaction-diffusion; simulation algorithm; modeling software
Ask authors/readers for more resources
Recent technological and theoretical advances are only now allowing the simulation of detailed kinetic models of biological systems that reflect the stochastic movement and reactivity of individual molecules within cellular compartments. The behavior of many systems could not be properly understood without this level of resolution, opening up new perspectives of using computer simulations to accelerate biological research. We review the modeling methodology applied to stochastic spatial models, also to the attention of non-expert potential users. Modeling choices, current limitations and perspectives of improvement of current general-purpose modeling/simulation platforms for biological systems are discussed. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available