Journal
MOLECULAR BRAIN RESEARCH
Volume 134, Issue 1, Pages 24-33Publisher
ELSEVIER
DOI: 10.1016/j.molbrainres.2004.09.028
Keywords
Parkinson's disease; progression; positron emission tomography
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Over the past two decades, positron emission tomography (PET) has provided valuable insights into the mechanisms of nigrostriatal degeneration in Parkinson's disease (PD). Furthermore, it allows the in vivo assessment of disease progression and the evaluation of treatment interventions. In this review, we shall discuss some of the issues and concerns that arise with the use of PET as a surrogate marker of disease progression in Parkinson's disease. (C) 2004 Elsevier B.V. All rights reserved.
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