Journal
BRITISH JOURNAL OF CANCER
Volume 92, Issue 6, Pages 1126-1129Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6602454
Keywords
peutz-jeghers syndrome; BRG1; STRAD alpha; MO25 alpha; LKB1
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Mutations in LKB1 lead to Peutz-Jeghers syndrome (PJS). However, only a subset of PJS patients harbours LKB1 mutations. We performed a mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRAD alpha, and MO25 alpha, in 28 LKB1-negative PJS patients. No disease-causing mutations were detected in the studied genes in PJS patients from different European populations.
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