Journal
PEDIATRIC ANESTHESIA
Volume 15, Issue 4, Pages 328-333Publisher
WILEY
DOI: 10.1111/j.1460-9592.2005.01417.x
Keywords
argatroban; heparin-induced thrombocytopenia; anticoagulation; cardiopulmonary bypass
Categories
Ask authors/readers for more resources
Heparin induced thrombocytopenia (HIT) is a rare, but potentially life-threatening complication of heparin therapy. In patients with HIT, alternative means of anticoagulation are necessary. The authors present an infant with HIT who required anticoagulation during cardiopulmonary bypass for tricuspid valve excision in the treatment of bacterial endocarditis. The direct thrombin inhibitor, argatroban, was successfully used. Previous reports regarding the use of argatroban and other nonheparin anticoagulants for anticoagulation are reviewed and suggestions regarding argatroban dosing in infants are presented.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available