Journal
LUNG CANCER
Volume 48, Issue 1, Pages 141-144Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.lungcan.2004.10.012
Keywords
epidermal growth factor receptor; gefitinib; small-cell lung cancer
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Gefitinib (Iressa, ZD1839) is an orally active inhibitor selective for the epidermal growth factor receptor tyrosine kinase and has shown promise in the treatment of non-small cell lung cancer (NSCLC). There has been no report to date of the effect of gefitinib treatment in patients with small-cell lung cancer (SCLC). Here we report a case of metastatic SCLC that was successfully treated with gefitinib. This case is the first reported of objective clinical response after gefitinib treatment in a patient with SCLC. Our report suggests that treatment with gefitinib is a novel option for a subset of patients with SCLC. (c) 2004 Elsevier Ireland Ltd. All rights reserved.
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