Constituents of holothuroidea, 14.: isolation and structure of new glucocerebroside molecular species from the sea cucumber Stichopus japonicus

Five glucocerebroside molecular species, SX-1-SX-5, have been isolated from the less polar lipid fraction of a chloroform/methanol extract of the sea cucumber Stich opus japonicus. The structures of these glucocerebroside molecular species were determined on the basis of chemical and spectroscopic evidence. SX-1, SJC-2, and SJC-3 are typical sphingosine- and phytosphingosine-type glucocerebroside molecular species with nonhydroxylated and hydroxylated fatty acyl moieties. SJC-4 and SJC-5 are also sphingosine-type glucocerebroside molecular species with hydroxylated fatty acyl moieties, although they are new glucocerebroside molecular species with unique sphingosine bases.