Journal
INFECTION AND IMMUNITY
Volume 73, Issue 4, Pages 2559-2563Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.73.4.2559-2563.2005
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Ring-stage parasitized erythrocytes (RPEs) were demonstrated to interact with effector cells of the innate immune system. With receptor blockade studies and CD36-null macrophages, human and murine macrophages were shown to phagocytose RPEs through the pattern recognition receptor CD36. These in vitro data implicate scavenger receptors in the clearance of RPEs.
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