Fast multidimensional NMR: Radial sampling of evolution space

Multidimensional NMR spectroscopy can be speeded up by limited radial sampling of the time-domain evolution data. The resulting frequency-domain projections are used to reconstruct the full NMR spectrum. New algorithms are proposed to suppress back-projection artifacts while retaining optimum sensitivity. The method is illustrated by experiments on the 900 MHz HNCO spectrum of a protein, HasA. (c) 2004 Elsevier Inc. All rights reserved.