4.3 Article

Synthesis and characterization of biologically potent Di-organotin(IV) complexes of mono-methyl glutarate

Journal

JOURNAL OF THE CHINESE CHEMICAL SOCIETY
Volume 52, Issue 2, Pages 231-236

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/jccs.200500034

Keywords

organotin(IV); complexes; mono-methyl glutarate; spectra; anti-bacterial; anti-inflammatory; acute toxicity

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The synthesis and characterization of some novel compounds of organotin(IV) chlorides with monomethyl glutarate is reported; the ligand molecule appears to be bound to the tin atom through the carbonyl oxygen. The results obtained through H-1-C-13-Sn-119 NMR, FT-IR and Sn-119 Mossbauer spectra show that the diorganotin(IV) complexes have hexacoordination with octahedral geometry. Biological screening of the complexes reveals that the di-organotin(IV) complexes show significant activity against all microorganisms.

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