Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 5, Issue 4, Pages 443-449Publisher
ASHLEY PUBLICATIONS LTD
DOI: 10.1517/14712598.5.4.443
Keywords
cancer; immunotherapy; Salmonella
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The use of bacteria for anticancer purposes was first attempted over 100 years ago. Recently, several strains of Salmonella have been shown to possess anticancer activity and, interestingly, Salmonella possesses a unique propensity to track to tumour tissue in vivo. This review presents the use of Salmonella for cancer immunotherapy, including the distinguishing characteristics of this organism and preclinical as well as clinical data.
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