Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 5, Issue 4, Pages 361-366Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557053544065
Keywords
antioxidants; immunisation; prion disease; therapeutics; transmissible spongiform encephalopathy (TSE)
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Prion diseases are of considerable importance because of the threat of a variant form of Creutzfeldt Jakob disease that has emerged in recent years. Pre-clinical diagnosis of prion diseases still remains poor and effective therapies also do not exist at present. This review examines research on possible therapeutic strategies that might have potential benefits if applied before neurodegeneration has occurred.
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