Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 347, Issue 5, Pages 667-672Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200404390
Keywords
asymmetric catalysis; hydrophosphorylation; palladium; P ligands; rhodium
Categories
Ask authors/readers for more resources
Regioselective and stereoselective hydrophosphorylation of vinylarenes 1 with pinacol H-phosphonate 2 can be achieved with transition metal catalysts. The use of rhodium catalysts such as the Wilkinson complex leads to the anti-Markovnikov adducts 3 as the only observable reaction products. In contrast, palladium catalysts give high selectivities for the Markovnikov adducts 4. In the presence of (R,S)-BINAPHOS as a chiral ligand, significant enantioselectivities have been obtained for the first time in hydrophosphorylation reactions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available