Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 16, Issue 2, Pages 167-173Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2005.01.005
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Among the many plant-based production systems that have been developed for pharmaceutical proteins, seeds have the useful advantage of accumulating proteins in a relatively small volume and in a stable environment in which they are protected from degradation. Several seed crops, including cereals, grain legumes and oilseeds, have been explored as production platforms, and the first commercial products - all technical proteins and enzymes - have already reached the market. Recent studies have explored the use of seeds for the production of pharmaceutical proteins, particularly replacement human proteins, recombinant antibodies and (oral) vaccines.
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