4.6 Article

Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-κB inhibitor, through downregulation of NFATc1

Journal

JOURNAL OF BONE AND MINERAL RESEARCH
Volume 20, Issue 4, Pages 653-662

Publisher

WILEY
DOI: 10.1359/JBMR.041213

Keywords

NF-kappa B; RANKL; NFATc1; osteoclastogenesis; bone resorption

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(-)-DHMEQ, a newly designed NF-kappa B inhibitor, inhibited RANKL-induced osteoclast differentiation in mouse BMMs through downregulation of the induction of NFATc1, an essential transcription factor of osteoclastogenesis.

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