Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 17, Issue 2, Pages 151-158Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2005.01.005
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Although NK cells were initially described as lymphocytes that lacked the characteristic markers of B and T cells, we now appreciate the plethora of activating and inhibitory receptors that define the NK cell surface phenotype. Recent studies have provided new insights into the molecular mechanisms that drive NK cell development, control the NK cell receptor repertoire and the cytokines that define the NK cell niche. These findings form the basis for an updated model of NK cell differentiation.
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