Journal
RADIOLOGY
Volume 235, Issue 1, Pages 218-228Publisher
RADIOLOGICAL SOC NORTH AMERICA
DOI: 10.1148/radiol.2351031663
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Funding
- NICHD NIH HHS [HD 39621] Funding Source: Medline
- NIDA NIH HHS [DA 015149] Funding Source: Medline
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Written informed consent was obtained prior to all human studies after the institutional review board approved the protocol. A continuous arterial spin-labeling technique with an amplitude-modulated control was implemented by using a single coil at 3.0 T. Adiabatic inversion efficiency at 3.0 T, comparable to that at 1.5 T, was achieved by reducing the amplitude of radiofrequency pulses and gradient strengths appropriately. The amplitude-modulated control provided a good match for the magnetization transfer effect of labeling pulses, allowing multisection perfusion magnetic resonance imaging of the whole brain. Comparison of multisection continuous and pulsed arterial spin-labeing methods at 3.0 T showed a 33% improvement in signal-to-noise ratio by using the former approach.
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