3.8 Article

Preference for and Satisfaction of Canadian Women With the Transdermal Contraceptive Patch Versus Previous Contraceptive Method: An Open-Label, Multicentre Study

Journal

JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA
Volume 27, Issue 4, Pages 350-359

Publisher

ELSEVIER INC
DOI: 10.1016/S1701-2163(16)30462-5

Keywords

Contracaption norelgestromin; ethinyl estradiol; transdermal contraceptive patch; EVRA; ORTHO EVRA

Funding

  1. Janssen-Ortho Inc., Toronto ON

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Objective: To document Canadian women's experience with the transdermal contraceptive patch, a method delivering 150 jig norelgestromin and 20 jig ethinyl estradiol daily. Methods: We conducted an open-label, multicentre, descriptive cohort study of the contraceptive patch over 9 cycles in 392 women requiring contraception. A single treatment cycle consisted of 3 consecutive 7-day patch applications followed by 1 patch-free week. At the final visit, overall satisfaction and preference for the patch was rated and compared with the previously used contraceptive method. Results: At baseline, 80.9% of participants were either very satisfied or somewhat satisfied with their previous contraceptive method, 89% having used oral contraceptives. At final observation, 60.6% of participants preferred the patch, 9.3% had no preference; and 30% preferred their previous method (n = 376). A total of 279 participants (71.2%) completed 9 cycles of patch use. Of these, 91% were satisfied with the patch and 74.9% preferred the patch to their previous contraceptive (43% strongly preferred and 31.9% preferred); 9% had no preference; and 16.1% preferred their previous method. Of those who preferred the patch, 82.7% preferred it because of its convenience or simplicity. Across all cycles, 88% of participants recorded perfect compliance. The most common adverse event was application site reactions (most of which were mild), experienced by 49% of participants: 33.7%, 16.5%, and 14.7% at cycles 1, 4, and 9, respectively. Conclusion: Both preference for and satisfaction with the transdermal contraceptive patch were high. Most participants found it easy to use and were highly compliant with the 7-day dosing regimen.

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