4.7 Article

CARHTAGene:: multipopulation integrated genetic and radiation hybrid mapping

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Car(h)(t)a Gene: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. Car(h)(t)a Gene: performs multipoint maximum likelihood estimations with accelerated expectation-maximization algorithms for some pedigrees and has sophisticated algorithms for marker ordering. Dedicated heuristics for framework mapping are also included. Car(h)(t)a Gene: can be used as a C++ library, through a shell command and a graphical interface. The XML output for companion tools is integrated.

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