4.4 Article

An easy access to unsymmetric trisubstituted methane derivatives (TRSMs)

Journal

TETRAHEDRON LETTERS
Volume 46, Issue 17, Pages 3097-3102

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.03.001

Keywords

TRAMs; FC reaction

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A new series of unsymmetric trisubstituted methane derivatives (TRSMs) has been synthesized through Friedel Crafts alkylation of aromatic nucleophiles using acid-sensitive heleroaryl carbinols. (c) 2005 Elsevier Ltd. All rights reserved.

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