Journal
PSYCHIATRY RESEARCH-NEUROIMAGING
Volume 138, Issue 3, Pages 269-272Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.pscychresns.2005.02.001
Keywords
Tourette's syndrome; functional magnetic resonance imaging; supplementary motor area; voluntary movement; motor task paradigm
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Tourette syndrome (TS) is hypothesised to be caused by an abnormal organization of movement control. The aim of this study was to use functional magnetic resonance imaging to study motor cortex activation in a TS patient. Usual and unusual self-paced voluntary movements were performed. The TS patient displayed supplementary motor area (SMA) activation during both tasks. This activation reflects a continuous use of the SMA to perform the voluntary motor movements required in both tasks. Moreover, the absence of tics during the execution of these voluntary motor tasks suggests that tic activity may be suppressed by additional mental effort. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
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