Journal
GYNECOLOGIC ONCOLOGY
Volume 97, Issue 2, Pages 318-322Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ygyno.2005.01.030
Keywords
risk factor; hysterectomy; ovarian cancer
Categories
Ask authors/readers for more resources
Objective. To analyze the role of hysterectomy, performed on benign indications. on the risk of developing ovarian cancer. Methods. Multicenter case-control study conducted in four Italian areas. Cases were 1031 women with epithelial ovarian cancer. Controls were 2411 women admitted to the same network of hospitals for a wide spectrum of acute non-neoplastic conditions, unrelated to known risk factors for ovarian cancer. Results. Compared to women with intact uterus and ovaries, the multivariate odds ratios (OR) was 0.6 (95% confidence interval 0.4-0.9) for women who reported hysterectomy. The OR was 0.5 >= 15 years after surgery. The OR was similar for women who had had pelvic surgery before age 45 and for those who had surgery later. No appreciable heterogeneity emerged across strata of parity and family history of ovarian breast cancer. Conclusion. Women who had undergone hysterectomy had a long-term reduced risk of epithelial ovarian cancer (c) 2005 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available