Journal
AMERICAN JOURNAL OF HEMATOLOGY
Volume 79, Issue 1, Pages 61-67Publisher
WILEY
DOI: 10.1002/ajh.20348
Keywords
sickle cell disease; bone marrow embolism; fat embolism; exchange transfusion; acute chest syndrome
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The fat embolism syndrome is an important complication of patients with sickle cell hemoglobinopathies because of severe morbidity and mortality. Our recent experience with three cases that survived with intensive supportive care and prompt use of transfusion stimulates this review. A high index of suspicion, prompt use of diagnostic tools, and aggressive clinical management are the keys to a successful outcome. Am. J. Hematol. 79:61-67, 2005. (c) 2005 Wiley-Liss, Inc.
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