Journal
CLINICAL MICROBIOLOGY AND INFECTION
Volume 11, Issue 5, Pages 372-378Publisher
ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2005.01127.x
Keywords
BACTEC TB-460; flow cytometric assay; Mycobacterium tuberculosis; proportion method; susceptibility testing; tuberculosis
Categories
Ask authors/readers for more resources
Tuberculosis is a leading cause of morbidity and mortality worldwide. Susceptibility testing of the causative agent, Mycobacterium tuberculosis, is critical for control of the disease. This study compared the flow cytometric susceptibility assay with the proportion method and the BACTEC TB-460 system. There was agreement between the flow cytometric and proportion methods for 73 (94%) of 78 isoniazid tests, and complete agreement for 26 ethambutol and rifampicin tests. In contrast, the proportion and BACTEC methods failed to agree for 22%, 15% and 8% of isoniazid, ethambutol and rifampicin tests, respectively. These findings indicated that susceptibility testing by the flow cytometric assay is accurate, with results available within 24 h of initiation of the testing procedure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available