The effect of anti-viral drug treatment of human immunodeficiency virus type 1 (HIV-1) described by a fractional order model

In this paper, generalized Euler method (GEM) and homotopy analysis method (HAM) are performed to solve the problem of the population dynamics of the human immunodeficiency type 1 virus (HIV-1). We introduce fractional orders to the model of HIV-1 whose components are plasma densities of uninfected CD4(+) T-cells, the infected such cells and the free virus. The effect of the drug treatment of HIV-1 will be discussed in this paper. (C) 2012 Elsevier Inc. All rights reserved.