Morphological analysis of mouse lungs after treatment with magnetite-based magnetic fluid stabilized with DMSA

Mouse lungs injected with magnetic fluids based on magnetite nanoparticles stabilized by 2,3-dimercaptosuccinic acid were studied. We observed clusters of magnetic nanoparticles inside blood vessels, within the organ parenchyma and cells, as well as increased numbers of leukocytes in the organ. Both the particle concentration and organ inflammation diminished in a time-dependent manner. (c) 2005 Elsevier B.V. All rights reserved.