Journal
BIOINFORMATICS
Volume 21, Issue 9, Pages 2140-2141Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bti269
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Funding
- NIAID NIH HHS [AI43649, AI50900] Funding Source: Medline
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EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries.
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