Journal
JOURNAL OF BACTERIOLOGY
Volume 187, Issue 10, Pages 3551-3555Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.187.10.3551-3555.2005
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Funding
- NIGMS NIH HHS [R01 GM058213, GM58213] Funding Source: Medline
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The toxin-coregulated pilus (TCP) of Vibrio cholerae is required for intestinal colonization and cholera toxin acquisition. Here we report that TCP mediates bacterial interactions required for biofilm differentiation on chitinaceous surfaces. We also show that undifferentiated TCP- biofilms have reduced ecological fitness and, thus, that chitin colonization may represent an ecological setting outside the host in which selection for a host colonization factor may take place.
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