Journal
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
Volume 293, Issue 1, Pages 501-508Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jmmm.2005.01.032
Keywords
magnetofection; gene therapy; gene delivery; magnetic drug targeting
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Magnetofection is nucleic acid delivery to cells supported and site-specifically guided by the attractive forces of magnetic fields acting on nucleic acid shuttles (vectors) which are associated with magnetic nanoparticles. Recent progress with the method confirms its general applicability with small and large nucleic acids and viruses. The method's therapeutic application as well as mechanistic studies will be discussed. (c) 2005 Elsevier B.V. All rights reserved.
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