Antitumor effect of magnetite nanoparticles in cat mammary adenocarcinoma

The antitumor effect of a magnetic fluid was studied after direct inoculation into cat mammary tumors. An external magnetic field was used to retain the nanoparticles in the tumor tissue. After 2 month, the mammary tumor regressed very much in size and the microscopic exam revealed that the tumor cells massively endocytosed magnetic nanoparticles and entered in lysis process. (c) 2005 Elsevier B.V. All rights reserved.