4.4 Article

Effect of the anticancer drug oracin on mouse liver topoisomerases I and II

Journal

JOURNAL OF PHARMACY AND PHARMACOLOGY
Volume 57, Issue 5, Pages 657-659

Publisher

WILEY
DOI: 10.1211/0022357055858

Keywords

-

Ask authors/readers for more resources

The inhibitory effect of oracin on the activities of topoisomerases I and II isolated from the nuclei of mice liver tissue was studied. This drug showed a 100% inhibitory effect at 5 mu M and 50% inhibition at 1 mu M on topoisomerase II activity, while the activity of topoisomerase I at these concentrations was not inhibited.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available