Journal
BIOLOGICAL PSYCHOLOGY
Volume 69, Issue 2, Pages 181-193Publisher
ELSEVIER
DOI: 10.1016/j.biopsycho.2004.07.005
Keywords
cortisol; EEG; frontal asymmetry; approach; avoidance; depression risk factor
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The acute effects of cortisol (35 mg) administration in 11 healthy male volunteers on resting frontal EEG asymmetry measured in the alpha band were investigated, using a within-subjects double-blind design. Results were indicative of a relative increase of right frontal activity with cortisol. This pattern of activity is similar to the deviant pattern that has been reported in patients suffering from depression, a condition often accompanied by elevated plasma cortisol levels. The significant effect on frontal asymmetry provides convergent support for our hypothesis, based upon previous results, that sustained (> 30 minutes after stress termination) relative high levels of cortisol inhibit approach motivation. (c) 2004 Elsevier B.V. All rights reserved.
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