Journal
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
Volume 293, Issue 1, Pages 731-736Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jmmm.2005.02.054
Keywords
magnetic microarray; MagArray; NanoTag; nanoparticles; spin valve; magnetic tunnel junction; biodetection; DNA detection
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We present proof-of-concept experiments and modeling towards a high-sensitivity magnetic microarray which tags a DNA fragment (or other biological samples) with a high-moment magnetic nanoparticle (NanoTag), which is in turn detected by a high-sensitivity spin valve (SV) or magnetic tunnel junction (MTJ) detector array. The detector can count the number of magnetic tags with a resolution of 1-20 magnetic NanoTags, potentially counting individual biomolecules. (c) 2005 Elsevier B.V. All rights reserved.
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