4.4 Article

Stereoselective total synthesis of (S)-Virol C and (S)-1-dehydroxyvirol A

Journal

TETRAHEDRON
Volume 61, Issue 19, Pages 4551-4556

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2005.03.014

Keywords

silicon and compounds; polyacetylenes; coupling reactions; enantioselective reductions

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A stereoselective total synthesis of (S)-Virol C and (S)-1-dehydroxyvirol A has been developed, based upon the selective and sequential substitution of the two trimethylsilyl groups of readily available 1,4-bis(trimethylsilyl)-1,3-butadiyne. (c) 2005 Elsevier Ltd. All rights reserved.

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