4.8 Article

Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts

Journal

ORGANIC LETTERS
Volume 7, Issue 10, Pages 1967-1969

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol050431s

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[GRAPHICS] Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.

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