Journal
FEMS MICROBIOLOGY LETTERS
Volume 246, Issue 2, Pages 191-198Publisher
OXFORD UNIV PRESS
DOI: 10.1016/j.femsle.2005.04.007
Keywords
Staphylococcus aureus; enterotoxin; multiplex PCR; genotyping; mobile genetic elements
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We describe a comprehensive detection system for 18 kinds of classical and newly described staphylococcal superantigenic toxin genes using four sets of multiplex PCR. Superantigenic toxin genotyping of Staphylococcus aureus for 69 food poisoning isolates and 97 healthy human nasal swab isolates revealed 32 superantigenic toxin genotypes and showed that many S. aureus isolates harbored multiple toxin genes. Analysis of the relationship between toxin genotypes and toxin genes encoding profiles of mobile genetic elements suggests its possible role in determining superantigenic toxin genotypes in S. aureus as combinations of toxin gene-encoding mobile genetic elements. (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
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