Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 15, Issue 10, Pages 2503-2507Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2005.03.068
Keywords
protein tyrosine phosphatase-1B; structure-based design
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Using structure-based design, a new class of inhibitors of protein tyrosine phosphatase-1B (PTP1B) has been identified, which incorporate the 1,2,5-thiadiazolidin-3-one-1, 1-dioxide template. (c) 2005 Elsevier Ltd. All rights reserved.
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