Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 1075, Issue 1-2, Pages 23-32Publisher
ELSEVIER
DOI: 10.1016/j.chroma.2005.04.013
Keywords
tetracycline antibiotics; biological matrix extraction; chromatography
Ask authors/readers for more resources
The extraction and cleanup of commonly used tetracyclines (oxytetracycline, tetracycline, chlortetracycline, and doxycycline) from sample matrix, and their subsequent determination via liquid chromatography can be problematic. Many manuscripts report on various challenges encountered when developing a method for tetracycline antibiotics determination. These complexities often result in less than perfect recoveries or chromatograms and are based on the underlying chemistry associated with tetracyclines. This review compiles, compares, and discusses the results and observations found in published methods, while focusing on chemical principles in order to increase the practicing chemist's understanding of TCs to aid him/her in developing useful analyses. Published by Elsevier B.V.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available