Journal
SYNTHESIS-STUTTGART
Volume -, Issue 8, Pages 1314-1318Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2005-861860
Keywords
fluoroalkyl-1,4,5-trisubstituted-1,2,3-triazole; one-pot reaction; regiospecific synthesis; fluoroalkylazide; terminal alkyne; 1,3-dipolar cycloaddition
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A method for the regiospecific synthesis of 1,4,5-trisubstituted-1,2,3-triazole catalyzed by copper(1) iodide was developed. This is the first example of it regiospecific synthesis of 5-iodo-1.4-disubstituted-1,2,3-triazole, which can be further elaborated to a range of 1,4,5-trisubstituted-1,2,3-triazole derivatives.
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