Journal
NEUROLOGY
Volume 64, Issue 10, Pages 1794-1796Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/01.WNL.0000161842.68793.8A
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Previously collected urine specimens from 100 patients referred to the UK National CJD Surveillance Unit as suspected cases of Creutzfeldt Jakob disease (CJD) were analyzed, testing for abnormal prion protein (PrPSc). In this context, the test had a low sensitivity and was not completely specific for CJD. Additionally, the proteins detected by this assay were not PrPSc but appeared to be immunoglobulins.
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