4.4 Article

Pd2(dba)3/Xantphos-catalyzed cross-coupling of thiols and aryl bromides/triflates

Journal

TETRAHEDRON
Volume 61, Issue 22, Pages 5253-5259

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2005.03.078

Keywords

palladium catalysis; thiol cross-coupling

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The cross-coupling of aliphatic and aromatic thiols and aryl bromides/triflates mediated by a Pd-2(dba)(3)/Xantphos catalytic system in refluxing xylene (140 degrees C) affords the corresponding aryl thioethers in good to excellent yields. (c) 2005 Elsevier Ltd. All rights reserved.

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