Journal
NEUROREPORT
Volume 16, Issue 8, Pages 859-863Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200505310-00016
Keywords
anterior cingulate gyrus; body mass index; calorie; eating; food; functional magnetic resonance imaging; limbic system; neuroimaging; orbitofrontal cortex
Categories
Funding
- NICHD NIH HHS [1R03 HD41542-01] Funding Source: Medline
Ask authors/readers for more resources
Little is known about the relationship between weight status and reward-related brain activity in normal weight humans. We correlated orbitofrontal and anterior cingulate cortex activity as measured by functional magnetic resonance imaging with body mass index in 13 healthy, normal-weight adult women as they viewed images of high-calorie and low-calorie foods, and dining-related utensils. Body mass index correlated negatively with both cingulate and orbitofrontal activity during high-calorie viewing, negatively with orbitofrontal activity during low-calorie viewing, and positively with orbitofrontal activity during presentations of nonedible utensils. With greater body mass, activity was reduced in brain regions important for evaluating and modifying learned stimulus-reward associations, suggesting a relationship between weight status and responsiveness of the orbitofrontal cortex to rewarding food images. NeuroReport 16:859-863 (c) 2005 Lippincott Williams & Wilkins.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available