Journal
THYROID
Volume 15, Issue 6, Pages 511-521Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/thy.2005.15.511
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Medullary thyroid cancer (MTC) is a prototypic neuroendocrine tumor of the thyroid C cells. Other than surgery, there are no curative therapies for MTC. In this review, we detail recent studies that suggest that targeting specific signaling pathways may be a viable strategy to control MTC tumor progression. Specifically, we discuss the role of the raf-1 and achaete-scute homologue-1 pathways in the MTC tumor growth and differentiation.
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