Journal
ANTIVIRAL RESEARCH
Volume 66, Issue 2-3, Pages 81-97Publisher
ELSEVIER
DOI: 10.1016/j.antiviral.2005.03.002
Keywords
anti-viral therapy; SARS-CoV; ribavirin
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A new disease, the severe acute respiratory distress syndrome (SARS), caused by the SARS coronavirus (SARS-CoV), emerged at the beginning of 2003 and rapidly spread throughout the world. Although the disease had disappeared in June 2003 its re-emergence cannot be excluded. The development of vaccines against SARS-CoV may take years. Therefore, the availability of effective antiviral drugs against SARS-CoV may be crucial for the control of future SARS outbreaks. In this review, experimental and clinical data about potential anti-SARS drugs is summarised and discussed. Animal model studies will be needed to help to determine which interventions warrant controlled clinical testing. (c) 2005 Elsevier B.V. All rights reserved.
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