4.6 Article

Analgesic and anti-inflammatory activity of Leonurus sibiricus

Journal

FITOTERAPIA
Volume 76, Issue 3-4, Pages 359-362

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2005.03.014

Keywords

Leonurus sibiricus; analgesic activity; anti-inflammatory activity

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The methanolic extract of Leonurus sibiricus aerial parts injected intraperitoneally at dose of 250 and 500 mg/kg showed a significant analgesic effect in acetic acid-induced writhing in mice. Moreover, when given orally to rats at dose of 200 and 400 mg/kg, it showed a significant anti-inflammatory activity against carrageenin induced rat paw edema in rats. (c) 2005 Elsevier B.V All rights reserved.

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