Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 382, Issue 4, Pages 926-933Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-005-3195-3
Keywords
silver nanotriangles; silver nanorods; anisotropic nanoparticles; metal-enhanced fluorescence; radiative decay engineering; increased excitation rate
Funding
- NCRR NIH HHS [P41 RR008119] Funding Source: Medline
- NIGMS NIH HHS [R21 GM070929, GM070929-01] Funding Source: Medline
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In this critical and timely review, the effects of anisotropic silver nanostructures on the emission intensity and photostability of a key fluorophore that is frequently used in many biological assays is examined. The silver nanostructures consist of triangular, rod-like, and fractal-like nanoparticles of silver deposited on conventional glass substrates. The close proximity to silver nanostructures results in greater intensity and photostability of the fluorophore than for fluorophores solely deposited on glass substrates. These new anisotropic silver nanostructure-coated surfaces show much more favorable effects than silver island films or silver colloidcoated substrates. Subsequently, the use of metal-enhanced fluorescence (MEF) for biosensing applications is discussed.
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