Journal
CLINICAL NUTRITION
Volume 24, Issue 3, Pages 462-465Publisher
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.clnu.2005.02.001
Keywords
taurolidine; lock solution; catheter infection; bloodstream infection
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The literature shows that repeated courses of antibiotics and catheter removals in a subset of patients suffering from multiple catheter-related bloodstream infections (CRBSI), are unlikely to prevent recurrence. In acceding to preventative strategies, we report our application of the antimicrobial chemotherapeutic Taurolidine used as a daily flush solution in seven home TPN patients suffering from multiple episodes. A pretreatment infection rate of 10.8 infections per 1000 catheter days decreased to 0.8 after treatment. (c) 2005 Elsevier Ltd. All rights reserved.
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