Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 5, Issue 6, Pages 563-574Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557054023233
Keywords
QSAR; natural and synthetic antioxidants; electronic effects
Categories
Ask authors/readers for more resources
During the last decade an increasing number of reports describe the roles of active oxygen species in the development or exacerbation of various kinds of diseases. Antioxidants are of great interest because of their involvement in important biological and industrial processes. They have been found to possess anticancer, anti-cardiovascular, anti-inflammatory and many other activities. Many attempts have been made to elucidate the QSAR of antioxidants by using different physicochemical parameters. Unfortunately the limited number of antioxidants and the unavailable sigma Hammett values of complex substituents did not lead to significant results in regression analysis. The redox potentials are well correlated to the antioxidant activities. In this report we will attempt to collect and discuss all the published results concerning the QSAR research on natural and synthetic antioxidants compounds.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available