Journal
FERTILITY AND STERILITY
Volume 83, Issue 6, Pages 1742-1744Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2004.11.078
Keywords
luteinizing hormone; premature surge; urinary LH kit; natural-cycle frozen-embryo transfer
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Objective: To determine the frequency and effect of premature luteinizing hormone (LH) surges on pregnancy rates in women with regular menstrual cycles. Design: Retrospective cohort study. Setting: Assisted Reproductive Technology Program at private medical college. Patient(s): Regularly menstruating women undergoing frozen embryo transfer (ET), Intervention(s): Detection of urinary LH surges with an RIA kit during natural-cycle frozen-embryos transfer. Main Outcome Measure(s): Incidence of premature LH surges and pregnancy outcomes. Result(s): Eighty-eight (46.8%) of 188 regularly menstruating women had premature LH surges and 33 (37%) of those 88 had multiple premature LH surges. Pregnancy rates per ET are similar between women with and without premature LH surges. Conclusion(S): A high percentage of normally cycling women demonstrate premature urinary LH surges without an effect on outcome of frozen-thawed ETs. (c) 2005 by American Society for Reproductive Medicine.
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